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Article

NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit.

Journal of cellular physiology - 1 Oct 2017

Wang Wei, Yi Mei, Chen Shengnan, Li Junjun, Zhang Haijing, Xiong Wei, Li Guiyuan, Li Xiaoling, Xiang Bo

Abstract excerpt

Cancer stem cells (CSCs) play a key role in tumor radiotherapy and chemotherapy resistance, relapse, and metastasis, and are primarily maintained in a resting state in vivo. The failure of conventional therapies to target CSCs is the main cause of treatment failure. The discovery of CSCs in nasopharyngeal carcinoma (NPC) tumors is becoming more prevalent; however, the understanding of the mechanisms underlying...

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PMID: 27891591
DOI: 10.1002/jcp.25706

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TCF4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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