Article
Epigenetic alterations of the BDNF gene in combat-related post-traumatic stress disorder.
Acta psychiatrica Scandinavica - 1 Feb 2017
Kim T Y, Kim S J, Chung H G, Choi J H, Kim S H, Kang J I
Abstract excerpt
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) plays a crucial role in modulating resilience and vulnerability to stress. The aim of this study was to investigate whether epigenetic regulation of the BDNF gene is a biomarker of post-traumatic stress disorder (PTSD) development among veterans exposed to combat in the Vietnam War. METHODS: Using the Clinician-Administered PTSD Scale, combat veterans were...
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