Article
Impairing both HMA4 homeologs is required for cadmium reduction in tobacco.
Plant, cell & environment - 1 Mar 2017
Liedschulte Verena, Laparra Hélène, Battey James Nicolas Duncan, Schwaar Joanne Deborah, Broye Hervé, Mark Régis, Klein Markus, Goepfert Simon, Bovet Lucien
Abstract excerpt
In tobacco, the heavy metal P1B-ATPases HMA4.1 and HMA4.2 function in root-to-shoot zinc and cadmium transport. We present greenhouse and field data that dissect the possibilities to impact the two homeologous genes in order to define the best strategy for leaf cadmium reduction. In a first step, both genes were silenced using an RNAi approach leading to >90% reduction of leaf cadmium content. To modulate HMA4...
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