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Triptolide inhibits tumor growth by induction of cellular senescence

18 Nov 2016

Abstract excerpt

Cellular senescence, an irreversible growth arrest of cells, is involved in protection against cancer. Triptolide (TPL) plays an important role in immunosuppressive, anti-fertility, anti-cystogenesis and anticancer activities. However, effect and mechanism of TPL on cellular senescence-associated antitumor is rarely reported. Herein HepG2 cells were used to explore the effect of TPL on tumor growth and cellular...

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PMID: 27878302
DOI: 10.3892/or.2016.5258

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