Article
RANK/RANKL/OPG pathway: genetic association with history of ischemic stroke in Italian population.
European review for medical and pharmacological sciences - 1 Nov 2016
Biscetti F, Giovannini S, Straface G, Bertucci F, Angelini F, Porreca C, Landolfi R, Flex A
Abstract excerpt
OBJECTIVE: RANKL is a member of the TNF superfamily that stimulates chemokine release, monocyte/macrophage matrix migration and matrix metalloproteinase activity and plays an important role in atherosclerosis. In our study, we have evaluated whether RANKL gene polymorphisms are involved in ischemic stroke in Italian subjects. PATIENTS AND METHODS: In a retrospective study we have included 487 patients (242 males,...
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