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Article

Reduced micro RNA ‐188‐3p expression contributes to apoptosis of spermatogenic cells in patients with azoospermia

21 Nov 2016

Abstract excerpt

BACKGROUND AND AIMS: Human mutL homologl (MLH1) works coordinately in sequential steps to initiate repair of DNA mismatches, and aberrant MLH1 expression is related to spermatogenetic malfunction. In the present study, MLH1 expression in patients with azoospermia was investigated, and moderating effects of miR-188-3p on MLH1 expression and spermatogenesis were identified. METHODS: Testicular tissues from 16...

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PMID: 27868267
DOI: 10.1111/cpr.12297

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