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Article

Multiethnic involvement in autosomal-dominant optic atrophy in Singapore.

Eye (London, England) - 1 Mar 2017

Loo J L, Singhal S, Rukmini A V, Tow S, Amati-Bonneau P, Procaccio V, Bonneau D, Gooley J J, Reynier P, Ferré M, Milea D

Abstract excerpt

PurposeAutosomal-dominant optic atrophy (ADOA), often associated with mutations in the OPA1 gene (chromosome 3q28-q29) is rarely reported in Asia. Our aim was to identify and describe this condition in an Asian population in Singapore.Patients and methodsPreliminary cross-sectional study at the Singapore National Eye Centre, including patients with clinical suspicion of ADOA, who subsequently underwent genetic...

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Source

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Identifiers

PMID: 27858935
DOI: 10.1038/eye.2016.255
PMCID: PMC5350376

Genes

OPA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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