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Article

A Genome-Wide Transcriptional Analysis of Yeast-Hyphal Transition in Candida tropicalis by RNA-Seq.

PloS one - 1 Jan 2016

Wu Yuan, Li Yin-Hu, Yu Shuan-Bao, Li Wen-Ge, Liu Xiao-Shu, Zhao Lei, Lu Jin-Xing

Abstract excerpt

Candida tropicalis is considered as the leading pathogen in nosocomial fungemia and hepatosplenic fungal infections in patients with cancer, particularly in leukemia. The yeast-filament transition is required for virulent infection by Candida. Several studies have explored the genome-wide transcription profile of Candida, however, no report on the transcriptional profile of C. tropicalis under yeast-filament...

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Identifiers

PMID: 27851809
DOI: 10.1371/journal.pone.0166645
PMCID: PMC5112795

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