Article
Combined effect of vascular endothelial growth factor and its receptor polymorphisms in endometriosis: a case-control study.
European journal of obstetrics, gynecology, and reproductive biology - 1 Feb 2017
Cardoso Jéssica Vilarinho, Abrão Maurício Simões, Vianna-Jorge Rosane, Ferrari Renato, Berardo Plínio Tostes, Machado Daniel Escorsim, Perini Jamila Alessandra
Abstract excerpt
OBJECTIVE: Endometriosis is a multifactorial gynecological disease, whose pathogenesis is crucially dependent on angiogenesis, which is signaled via vascular endothelial growth factor (VEGF) and its receptor (VEGFR2). We hypothesize that single nucleotide polymorphisms (SNPs) in VEGF and VEGFR2 genes may influence the onset and/or the progression of endometriosis. The main aim of this study was to investigate the...
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