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Hierarchical lncRNA regulatory network in early-onset severe preeclampsia

29 Jul 2024

Abstract excerpt

BACKGROUND: Recent studies have shown that several long non-coding RNAs (lncRNAs) in the placenta are associated with preeclampsia (PE). However, the extent to which lncRNAs may contribute to the pathological progression of PE is unclear. RESULTS: Here, we report a hierarchical regulatory network involved in early-onset severe PE (EOSPE). We have carried out transcriptome sequencing on the placentae from patients...

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PMID: 39075446
DOI: 10.1186/s12915-024-01959-1

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