Article
Exogenous iodide ameliorates perchlorate-induced thyroid phenotypes in threespine stickleback.
General and comparative endocrinology - 1 Mar 2017
Gardell Alison M, von Hippel Frank A, Adams Elise M, Dillon Danielle M, Petersen Ann M, Postlethwait John H, Cresko William A, Buck C Loren
Abstract excerpt
Perchlorate is a ubiquitous environmental contaminant that has widespread endocrine disrupting effects in vertebrates, including threespine stickleback (Gasterosteus aculeatus). The target of perchlorate is thyroid tissue where it induces changes in the organization, activation, and morphology of thyroid follicles and surrounding tissues. To test the hypothesis that some phenotypes of perchlorate toxicity are not...
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