Article
Personalized Treatment for a Patient With a BRAF V600E Mutation Using Dabrafenib and a Tumor Treatment Fields Device in a High-Grade Glioma Arising From Ganglioglioma.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Nov 2016
Meletath Silviya K, Pavlick Dean, Brennan Tim, Hamilton Roy, Chmielecki Juliann, Elvin Julia A, Palma Norma, Ross Jeffrey S, Miller Vincent A, Stephens Philip J, Snipes George, Rajaram Veena, Ali Siraj M, Melguizo-Gavilanes Isaac
Abstract excerpt
BACKGROUND: Gangliogliomas are slow-growing, low-grade central nervous system tumors affecting children and young adults. However, some patients will experience tumor recurrence and/or malignant progression. This article reports on the clinical history, molecular findings, and treatment response in a patient with BRAF V600-mutated high-grade glioma arising from ganglioglioma. METHODS: Hematoxylin-eosin staining...
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