Article
Diversity of polymyxin resistance mechanisms among Acinetobacter baumannii clinical isolates.
Diagnostic microbiology and infectious disease - 1 Jan 2017
Girardello Raquel, Visconde Marina, Cayô Rodrigo, Figueiredo Regina Célia Bressan Queiroz de, Mori Marcelo Alves da Silva, Lincopan Nilton, Gales Ana Cristina
Abstract excerpt
Polymyxins have become drugs of last resort for treatment of multi-drug resistant (MDR) Gram-negative infections. However, the mechanisms of resistance to this compound have not been completely elucidated. In this study, we evaluated the mechanisms of resistance to this antimicrobial in two A. baumannii clinical isolates, respectively, susceptible (A027) and resistant (A009) to polymyxin B before and after...
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