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Article

Use of next generation sequence to investigate potential novel macrolide resistance mechanisms in a population of Moraxella catarrhalis isolates.

Scientific reports - 24 Oct 2016

Liu Ya-Li, Li Dong-Fang, Xu He-Ping, Xiao Meng, Cheng Jing-Wei, Zhang Li, Xu Zhi-Peng, Chen Xin-Xin, Zhang Ge, Kudinha Timothy, Kong Fanrong, Gong Yan-Ping, Wang Xin-Ying, Zhang Yin-Xin, Wu Hong-Long, Xu Ying-Chun

Abstract excerpt

Although previous studies have confirmed that 23S rRNA gene mutation could be responsible for most of macrolide resistance in M. catarrhalis, a recent study suggested otherwise. Next generation sequence based comparative genomics has revolutionized the mining of potential novel drug resistant mechanisms. In this study, two pairs of resistant and susceptible M. catarrhalis isolates with different multilocus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27774989
DOI: 10.1038/srep35711
PMCID: PMC5075928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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