Article
CDKN2B Methylation and Aortic Arch Calcification in Patients with Ischemic Stroke.
Journal of atherosclerosis and thrombosis - 1 Jun 2017
Zhou Shuyu, Cai Biyang, Zhang Zhizhong, Zhang Yumeng, Wang Li, Liu Keting, Zhang Hao, Sun Lingli, Cai Huan, Lu Guangming, Liu Xinfeng, Xu Gelin
Abstract excerpt
AIM: CDKN2A/2B near chromosome 9p21 has been proposed as a potential genetic etiology for both atherosclerosis and arterial calcification. DNA methylation, which can change the expression of CDKN2A/2B, may be an underlying mechanism for this association. This study aimed to evaluate whether CDKN2A/2B methylation is related to aortic arch calcification (AAC) in patients with ischemic stroke. METHODS: DNA...
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