Article
Associations of Prolonged QTc in Sickle Cell Disease.
PloS one - 1 Jan 2016
Indik Julia H, Nair Vineet, Rafikov Ruslan, Nyotowidjojo Iwan S, Bisla Jaskanwal, Kansal Mayank, Parikh Devang S, Robinson Melissa, Desai Anand, Oberoi Megha, Gupta Akash, Abbasi Taimur, Khalpey Zain, Patel Amit R, Lang Roberto M, Dudley Samuel C, Choi Bum-Rak, Garcia Joe G N, Machado Roberto F, Desai Ankit A
Abstract excerpt
Sudden death is a leading cause of mortality in sickle cell disease, implicating ventricular tachyarrhythmias. Prolonged QTc on an electrocardiogram (ECG), commonly seen with myocardial ischemia, is a known risk for polymorphic ventricular tachycardia (VT). We hypothesized that prolonged QTc is associated with mortality in sickle cell disease. ECG were analyzed from a cohort of 224 sickle patients (University of...
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