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Article

Analysis of genetic and non genetic risk factors for cisplatin ototoxicity in pediatric patients.

International journal of pediatric otorhinolaryngology - 1 Nov 2016

Olgun Yüksel, Aktaş Safiye, Altun Zekiye, Kırkım Günay, Kızmazoğlu Deniz Çakır, Erçetin Ayşe Pınar, Demir Banu, İnce Dilek, Mutafoğlu Kamer, Demirağ Bengü, Ellidokuz Hülya, Olgun Nur, Güneri Enis Alpin

Abstract excerpt

OBJECTIVE: The aim of this study was to analyse the genetic and non genetic risk factors for cisplatin ototoxicity. METHODS: This study was conducted on 72 children who received cisplatin based chemotherapy. Brock and Muenster classifications were used to evaluate ototoxicity seen in these children. 6 single nucleotide polymorphisms (SNP); ERCC1 rs 11615, GSTP1 rs1138272, GSTP1 rs1695, LRP2 rs 2075252, TPMT rs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27729156
DOI: 10.1016/j.ijporl.2016.09.001

Genes

GSTP1
COMT
ERCC1
LRP2
TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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