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Article

Genetic risk factors of cisplatin induced ototoxicity in adult patients.

Neoplasma - 1 Jan 2016

Talach T, Rottenberg J, Gal B, Kostrica R, Jurajda M, Kocak I, Lakomy R, Vogazianos E

Abstract excerpt

Ototoxicity is an important adverse effect of using Cisplatin (cis-diamminedichloroplatinum) (CDDP) as a form of chemotherapy. The clinical picture of CDDP induced ototoxicity includes perceptive hearing impairment (reversible or permanent) and tinnitus. Ototoxicity manifests with considerable variability between patients. The objective of this prospective study was to investigate a possible genetic background to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26774148
DOI: 10.4149/212_140820N391

Genes

COMT
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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