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Article

Rationale for RAS mutation-tailored therapies.

Future oncology (London, England) - 1 Feb 2017

Montalvo Steven K, Li Lianbo, Westover Kenneth D

Abstract excerpt

RAS mutations are among the most common genetic alterations found in cancerous tumors but rational criteria or strategies for targeting RAS-dependent tumors are only recently emerging. Clinical and laboratory data suggest that patient selection based on specific RAS mutations will be an essential component of these strategies. A thorough understanding of the biochemical and structural properties of mutant RAS...

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Source

Identifiers

PMID: 27728979
DOI: 10.2217/fon-2016-0363

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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