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Article

Glycosynthase mediated synthesis of psychosine.

Carbohydrate research - 29 Nov 2016

Goddard-Borger Ethan D, Tysoe Christina, Withers Stephen G

Abstract excerpt

Globoid cell leukodystrophy (GCL), or Krabbe disease, is a lysosomal storage disorder characterized by a deficiency in galactosylceramidase (GALC), which hydrolyses galactosylceramide and galactosylsphingosine (psychosine). Early detection of GCL in newborns is essential for timely therapeutic intervention and could be achieved by testing infant blood samples with isotopically labeled lysosmal enzyme substrates...

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Source

Identifiers

PMID: 27721144
DOI: 10.1016/j.carres.2016.09.013

Genes

GALC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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