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Article

Making extra teeth: Lessons from a TRPS1 mutation.

American journal of medical genetics. Part A - 1 Jan 2017

Kunotai Worawan, Ananpornruedee Panjit, Lubinsky Mark, Pruksametanan Apitchaya, Kantaputra Piranit Nik

Abstract excerpt

A Thai mother and her two daughters were affected with tricho-rhino-phalangeal syndrome type I. The daughters had 15 and 18 supernumerary teeth, respectively. The mother had normal dentition. Mutation analysis of TRPS1 showed a novel heterozygous c.3809_3811delACTinsCATGTTGTG mutation in all. This mutation is predicted to cause amino acid changes in the Ikaros-like zinc finger domain near the C-terminal end of...

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Source

Identifiers

PMID: 27706911
DOI: 10.1002/ajmg.a.37967

Genes

TRPS1
APC
RUNX2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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