Article
Visual Acuity Change Over 24 Months and Its Association With Foveal Phenotype and Genotype in Individuals With Stargardt Disease: ProgStar Study Report No. 10.
JAMA ophthalmology - 1 Aug 2018
Kong Xiangrong, Fujinami Kaoru, Strauss Rupert W, Munoz Beatriz, West Sheila K, Cideciyan Artur V, Michaelides Michel, Ahmed Mohamed, Ervin Ann-Margret, Schönbach Etienne, Cheetham Janet K, Scholl Hendrik P N
Abstract excerpt
Importance: Limited data from prospective studies are available to understand the natural history of ABCA4-related Stargardt disease (STGD1). Such data are important for determining appropriate outcome measures for future STGD1 trials. Objective: To estimate the rate of loss of best-corrected visual acuity (BCVA) during 2 years and to estimate the associations of BCVA loss with foveal phenotype and genotype in...
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