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Article

Low expression of galectin-3 is associated with poor survival in node-positive breast cancers and mesenchymal phenotype in breast cancer stem cells.

Breast cancer research : BCR - 29 Sept 2016

Ilmer Matthias, Mazurek Nachman, Gilcrease Michael Z, Byrd James C, Woodward Wendy A, Buchholz Thomas A, Acklin Kim, Ramirez Karen, Hafley Margarete, Alt Eckhard, Vykoukal Jody, Bresalier Robert S

Abstract excerpt

BACKGROUND: Galectin-3 (Gal3) plays diverse roles in cancer initiation, progression, and drug resistance depending on tumor type characteristics that are also associated with cancer stem cells (CSCs). Recurrence of breast carcinomas may be attributed to the presence of breast CSCs (BCSCs). BCSCs exist in mesenchymal-like or epithelial-like states and the transition between these states endows BCSCs with the...

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Identifiers

PMID: 27687248
DOI: 10.1186/s13058-016-0757-6
PMCID: PMC5043623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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