Article
Urgent Implementation in a Hospital Setting of a Strategy To Rule Out Secondary Cases Caused by Imported Extensively Drug-Resistant Mycobacterium tuberculosis Strains at Diagnosis.
Journal of clinical microbiology - 1 Dec 2016
Pérez-Lago Laura, Martínez-Lirola Miguel, García Sergio, Herranz Marta, Mokrousov Igor, Comas Iñaki, Martínez-Priego Llúcia, Bouza Emilio, García-de-Viedma Darío
Abstract excerpt
Current migratory movements require new strategies for rapidly tracking the transmission of high-risk imported Mycobacterium tuberculosis strains. Whole-genome sequencing (WGS) enables us to identify single-nucleotide polymorphisms (SNPs) and therefore design PCRs to track specific relevant strains. However, fast implementation of these strategies in the hospital setting is difficult because professionals working...
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