Article
Pretreatment AKR1B10 expression predicts the risk of hepatocellular carcinoma development after hepatitis C virus eradication.
World journal of gastroenterology - 7 Sept 2016
Murata Ayato, Genda Takuya, Ichida Takafumi, Amano Nozomi, Sato Sho, Tsuzura Hironori, Sato Shunsuke, Narita Yutaka, Kanemitsu Yoshio, Shimada Yuji, Hirano Katsuharu, Iijima Katsuyori, Wada Ryo, Nagahara Akihito, Watanabe Sumio
Abstract excerpt
AIM: To clarify the association between aldo-keto reductase family 1 member B10 (AKR1B10) expression and hepatocarcinogenesis after hepatitis C virus eradication. METHODS: In this study, we enrolled 303 chronic hepatitis C patients who had achieved sustained virological response (SVR) through interferon-based antiviral therapy. Pretreatment AKR1B10 expression in the liver was immunohistochemically assessed and...
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