Article
Zinc availability during germline development impacts embryo viability in Caenorhabditis elegans.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Jan 2017
Mendoza Adelita D, Woodruff Teresa K, Wignall Sarah M, O'Halloran Thomas V
Abstract excerpt
Zinc is an essential metal that serves as a cofactor in a variety of cellular processes, including meiotic maturation. Cellular control of zinc uptake, availability and efflux is closely linked to meiotic progression in rodent and primate reproduction where large fluctuations in zinc levels are critical at several steps in the oocyte-to-embryo transition. Despite these well-documented roles of zinc fluxes during...
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