Article
Seeding and Establishment of Legionella pneumophila in Hospitals: Implications for Genomic Investigations of Nosocomial Legionnaires' Disease.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 May 2017
David Sophia, Afshar Baharak, Mentasti Massimo, Ginevra Christophe, Podglajen Isabelle, Harris Simon R, Chalker Victoria J, Jarraud Sophie, Harrison Timothy G, Parkhill Julian
Abstract excerpt
Background: Legionnaires' disease is an important cause of hospital-acquired pneumonia and is caused by infection with the bacterium Legionella. Because current typing methods often fail to resolve the infection source in possible nosocomial cases, we aimed to determine whether whole-genome sequencing (WGS) could be used to support or refute suspected links between cases and hospitals. We focused on cases...
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