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Article

Do metabolic derangements in end-stage polycystic kidney disease differ versus other primary kidney diseases?

Nephrology (Carlton, Vic.) - 1 Jan 2018

Jankowska Magdalena, Qureshi Abdul Rashid, Barany Peter, Heimburger Olof, Stenvinkel Peter, Lindholm Bengt

Abstract excerpt

AIM: Autosomal dominant polycystic kidney disease (ADPKD), a systemic disorder caused by mutation in genes encoding polycystins, has been reported to lead to metabolic derangements including new-onset diabetes mellitus after kidney transplantation. We analyzed markers of insulin resistance (IR), inflammation, nutritional status and insulin-like growth factor-1 (IGF-1) in end-stage renal disease (ESRD) patients...

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Identifiers

PMID: 27653449
DOI: 10.1111/nep.12927

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