Article
Identifying and annotating human bifunctional RNAs reveals their versatile functions.
Science China. Life sciences - 1 Oct 2016
Chen Geng, Yang Juan, Chen Jiwei, Song Yunjie, Cao Ruifang, Shi Tieliu, Shi Leming
Abstract excerpt
Bifunctional RNAs that possess both protein-coding and noncoding functional properties were less explored and poorly understood. Here we systematically explored the characteristics and functions of such human bifunctional RNAs by integrating tandem mass spectrometry and RNA-seq data. We first constructed a pipeline to identify and annotate bifunctional RNAs, leading to the characterization of 132 high-confidence...
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