Heterotrisomy recurrence risk: a practical maternal age-dependent approach for excess trisomy 21 risk calculation after a previous autosomal trisomy

Abstract excerpt

A new maternal age-dependent method to estimate absolute excess risks of trisomy 21, either after a previous trisomy 21 (homotrisomy) or after another trisomy (heterotrisomy), is proposed to be added to the estimated risk by conventional screening methods. Excess risk at term for a subsequent trisomy 21 was calculated from midtrimester risks reported by Morris et al., decreasing from 0.49% at 20 years to 0.01% at...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Pregnancy and preeclampsia studies
• Share to Prenatal Screening and Diagnostics
• Share to Urological Disorders and Treatments