New insights into the genetic component of non-infectious uveitis through an Immunochip strategy.

doi:10.1136/jmedgenet-2016-104144

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Article

New insights into the genetic component of non-infectious uveitis through an Immunochip strategy.

Journal of medical genetics - 1 Jan 2017

Márquez Ana, Cordero-Coma Miguel, Martín-Villa José Manuel, Gorroño-Echebarría Marina Begoña, Blanco Ricardo, Díaz Valle David, Del Rio María José, Blanco Ana, Olea Jose Luis, Cordero Yolanda, Capella María José, Díaz-Llopis Manuel, Ortego-Centeno Norberto, Ruiz-Arruza Ioana, Llorenç Víctor, Adán Alfredo, Fonollosa Alejandro, Ten Berge Josianne, Atan Denize, Dick Andrew D, De Boer Joke H, Kuiper Jonas, Rothova Aniki, Martín Javier

Abstract excerpt

BACKGROUND: Large-scale genetic studies have reported several loci associated with specific disorders involving uveitis. Our aim was to identify genetic risk factors that might predispose to uveitis per se, independent of the clinical diagnosis, by performing a dense genotyping of immune-related loci. METHODS: 613 cases and 3693 unaffected controls from three European case/control sets were genotyped using the...

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PMID: 27609017
DOI: 10.1136/jmedgenet-2016-104144

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