Article
The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases.
International journal of radiation oncology, biology, physics - 1 Oct 2016
Sperduto Paul W, Yang T Jonathan, Beal Kathryn, Pan Hubert, Brown Paul D, Bangdiwala Ananta, Shanley Ryan, Yeh Norman, Gaspar Laurie E, Braunstein Steve, Sneed Penny, Boyle John, Kirkpatrick John P, Mak Kimberley S, Shih Helen A, Engelman Alex, Roberge David, Arvold Nils D, Alexander Brian, Awad Mark M, Contessa Joseph, Chiang Veronica, Hardie John, Ma Daniel, Lou Emil, Sperduto William, Mehta Minesh P
Abstract excerpt
PURPOSE: Lung cancer remains the most common cause of both cancer mortality and brain metastases (BM). The purpose of this study was to assess the effect of gene alterations and tyrosine kinase inhibition (TKI) on median survival (MS) and cause of death (CoD) in patients with BM from lung adenocarcinoma (L-adeno). METHODS: A multi-institutional retrospective database of patients with L-adeno and newly diagnosed...
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