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Corticosteroid therapy in assisted reproduction – immune suppression is a faulty premise

2 Sept 2016

Abstract excerpt

There is ongoing interest in immune-suppressant corticosteroid drugs such as prednisolone to treat infertility in women with repeated IVF failure and recurrent miscarriage. The rationale draws on the pervasive but flawed view that immune activation is inconsistent with normal pregnancy. This ignores clear evidence that controlled inflammation and activation of the immune response is essential for embryo...

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PMID: 27591233
DOI: 10.1093/humrep/dew186

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