Article
Ponatinib in the therapy of chronic myeloid leukemia.
Expert review of hematology - 1 Oct 2016
Poch Martell Marc, Sibai Hassan, Deotare Uday, Lipton Jeffrey H
Abstract excerpt
INTRODUCTION: Chronic Myeloid Leukemia (CML) is a myeloproliferative disorder that has become the neoplastic poster child for understanding the disease biology of a malignant disease and targeting effective therapy. The targeted therapy of BCR-ABL inhibition by tyrosine kinase inhibitors (TKI) has provided the epitome for "Ehlrich's magic bullet" postulated decades ago. AREAS COVERED: Due to the therapy with...
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