Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts

Abstract excerpt

Preeclampsia (PE) is a placenta-induced inflammatory disease associated with maternal and fetal morbidity and mortality. The mechanisms underlying PE remain enigmatic and delivery of the placenta is the only known remedy. PE is associated with coagulation and platelet activation and increased extracellular vesicle (EV) formation. However, thrombotic occlusion of the placental vascular bed is rarely observed and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Extracellular vesicles in disease
• Share to Pregnancy and preeclampsia studies
• Share to Reproductive System and Pregnancy