MicroRNA analysis of medium/large placenta extracellular vesicles in normal and preeclampsia pregnancies

Abstract excerpt

Background Preeclampsia (PE) is a hypertensive disorder of pregnancy, affecting 2%–8% of pregnancies worldwide, and is the leading cause of adverse maternal and fetal outcomes. The disease is characterized by oxidative and cellular stress and widespread endothelial dysfunction. While the precise mechanisms are not entirely understood, the pathogenesis of PE is closely linked to placental dysfunction and, to some...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Extracellular vesicles in disease
• Share to Pregnancy and preeclampsia studies
• Share to Reproductive System and Pregnancy