Article
Simultaneous discovery of cancer subtypes and subtype features by molecular data integration.
Bioinformatics (Oxford, England) - 1 Sept 2016
Le Van Thanh, van Leeuwen Matthijs, Carolina Fierro Ana, De Maeyer Dries, Van den Eynden Jimmy, Verbeke Lieven, De Raedt Luc, Marchal Kathleen, Nijssen Siegfried
Abstract excerpt
MOTIVATION: Subtyping cancer is key to an improved and more personalized prognosis/treatment. The increasing availability of tumor related molecular data provides the opportunity to identify molecular subtypes in a data-driven way. Molecular subtypes are defined as groups of samples that have a similar molecular mechanism at the origin of the carcinogenesis. The molecular mechanisms are reflected by...
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