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Recombinant human oviductin regulates protein tyrosine phosphorylation and acrosome reaction

31 Aug 2016

Abstract excerpt

The mammalian oviduct synthesizes and secretes a major glycoprotein known as oviductin (OVGP1), which has been shown to interact with gametes and early embryos. Here we report the use of recombinant DNA technology to produce, for the first time, the secretory form of human OVGP1 in HEK293 cells. HEK293 colonies stably expressing recombinant human OVGP1 (rHuOVGP1) were established by transfecting cells with an...

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PMID: 27581080
DOI: 10.1530/rep-16-0177

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