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Article

Heat Shock 70 Protein Genes and Genetic Susceptibility to Apical Periodontitis.

Journal of endodontics - 1 Oct 2016

Maheshwari Kanwal, Silva Renato M, Guajardo-Morales Leticia, Garlet Gustavo P, Vieira Alexandre R, Letra Ariadne

Abstract excerpt

INTRODUCTION: Heat shock proteins (HSPs) protect cells under adverse conditions such as infection, inflammation, and disease. The differential expression of HSPs in human periapical granulomas suggests a potential role for these proteins in periapical lesion development, which may contribute to different clinical outcomes. Therefore, we hypothesized that polymorphisms in HSP genes leading to perturbed gene...

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Identifiers

PMID: 27567034
DOI: 10.1016/j.joen.2016.07.010
PMCID: PMC5035602

Genes

HSPA6
HSPA4
HSPA9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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