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Article

Declined Expression of Histone Deacetylase 6 Contributes to Periodontal Ligament Stem Cell Aging.

Journal of periodontology - 1 Jan 2017

Li Qian, Ma Yushi, Zhu Yunyan, Zhang Ting, Zhou Yanheng

Abstract excerpt

BACKGROUND: Identification of regulators for aging-associated stem cell (SC) dysfunctions is a critical topic in SC biology and SC-based therapies. Periodontal ligament stem cell (PDLSC), a kind of dental mesenchymal SC with dental regeneration potential, ages with functional deterioration in both in vivo and ex vivo expansion. However, little is known about regulators for PDLSC aging. METHODS: Expression changes...

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Identifiers

PMID: 27562218
DOI: 10.1902/jop.2016.160338

Genes

HDAC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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