Article
Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape.
PLoS genetics - 1 Aug 2016
Cole Joanne B, Manyama Mange, Kimwaga Emmanuel, Mathayo Joshua, Larson Jacinda R, Liberton Denise K, Lukowiak Ken, Ferrara Tracey M, Riccardi Sheri L, Li Mao, Mio Washington, Prochazkova Michaela, Williams Trevor, Li Hong, Jones Kenneth L, Klein Ophir D, Santorico Stephanie A, Hallgrimsson Benedikt, Spritz Richard A
Abstract excerpt
The human face is a complex assemblage of highly variable yet clearly heritable anatomic structures that together make each of us unique, distinguishable, and recognizable. Relatively little is known about the genetic underpinnings of normal human facial variation. To address this, we carried out a large genomewide association study and two independent replication studies of Bantu African children and adolescents...
Topics
- 3',5'-Cyclic-AMP Phosphodiesterases
- Adolescent
- Animals
- Black People
- Carrier Proteins
- Face
- Female
- Genome-Wide Association Study
- Humans