An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women.

doi:10.1186/s12863-016-0428-8

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Article

An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women.

BMC genetics - 24 Aug 2016

Karppanen Tiina, Kaartokallio Tea, Klemetti Miira M, Heinonen Seppo, Kajantie Eero, Kere Juha, Kivinen Katja, Pouta Anneli, Staff Anne Cathrine, Laivuori Hannele

Abstract excerpt

BACKGROUND: Preeclampsia is a common and heterogeneous vascular syndrome of pregnancy. Its genetic risk profile is yet unknown and may vary between individuals and populations. The rs4606 3' UTR polymorphism of the Regulator of G-protein signaling 2 gene (RGS2) in the mother has been implicated in preeclampsia as well as in the development of chronic hypertension after preeclampsia. The RGS2 protein acts as an...

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PMID: 27558088
DOI: 10.1186/s12863-016-0428-8
PMCID: PMC4997762

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RGS2

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