Article
Systems Biology and Clinical Practice in Respiratory Medicine. The Twain Shall Meet.
American journal of respiratory and critical care medicine - 1 Nov 2016
Thamrin Cindy, Frey Urs, Kaminsky David A, Reddel Helen K, Seely Andrew J E, Suki Béla, Sterk Peter J
Abstract excerpt
Respiratory diseases are highly complex, being driven by host-environment interactions and manifested by inflammatory, structural, and functional abnormalities that vary over time. Traditional reductionist approaches have contributed vastly to our knowledge of biological systems in health and disease to date; however, they are insufficient to provide an understanding of the behavior of the system as a whole. In...
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