Addressing the complexity of chronic obstructive pulmonary disease: from phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine.

doi:10.1164/rccm.201009-1414PP

Back to search

Article

Addressing the complexity of chronic obstructive pulmonary disease: from phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine.

American journal of respiratory and critical care medicine - 1 May 2011

Agusti Alvar, Sobradillo Patricia, Celli Bartolomé

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a complex disease at the clinical, cellular, and molecular levels. However, its diagnosis, assessment, and therapeutic management are based almost exclusively on the severity of airflow limitation. A better understanding of the multiple dimensions o...

Topics

Biomarkers
Humans
Phenotype
Precision Medicine
Pulmonary Disease, Chronic Obstructive
Systems Biology

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.