Article
Bacteroides fragilis type VI secretion systems use novel effector and immunity proteins to antagonize human gut Bacteroidales species.
Proceedings of the National Academy of Sciences of the United States of America - 29 Mar 2016
Chatzidaki-Livanis Maria, Geva-Zatorsky Naama, Comstock Laurie E
Abstract excerpt
Type VI secretion systems (T6SSs) are multiprotein complexes best studied in Gram-negative pathogens where they have been shown to inhibit or kill prokaryotic or eukaryotic cells and are often important for virulence. We recently showed that T6SS loci are also widespread in symbiotic human gut bacteria of the order Bacteroidales, and that these T6SS loci segregate into three distinct genetic architectures (GA)....
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