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Article

Serum versus Imaging Biomarkers in Friedreich Ataxia to Indicate Left Ventricular Remodeling and Outcomes.

Texas Heart Institute journal - 1 Aug 2016

Mehta Nishaki, Chacko Paul, Jin James, Tran Tam, Prior Thomas W, He Xin, Agarwal Gunjan, Raman Subha V

Abstract excerpt

Patients with Friedreich ataxia typically die of cardiomyopathy, marked by myocardial fibrosis and abnormal left ventricular (LV) geometry. We measured procollagen I carboxyterminal propeptide (PICP), a serum biomarker of collagen production, and characterized genotypes, phenotypes, and outcomes in these patients. Twenty-nine patients with Friedreich ataxia (mean age, 34.2 ± 2.2 yr) and 29 healthy subjects (mean...

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Source

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Identifiers

PMID: 27547137
DOI: 10.14503/THIJ-14-4198
PMCID: PMC4979385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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