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Article

Oncolytic virus efficiency inhibited growth of tumour cells with multiple drug resistant phenotype in vivo and in vitro.

Journal of translational medicine - 18 Aug 2016

Goncharova Elena P, Ruzhenkova Julia S, Petrov Ivan S, Shchelkunov Sergey N, Zenkova Marina A

Abstract excerpt

BACKGROUND: Tumour resistance to a wide range of drugs (multiple drug resistant, MDR) acquired after intensive chemotherapy is considered to be the main obstacle of the curative treatment of cancer patients. Recent work has shown that oncolytic viruses demonstrated prominent potential for effective treatment of diverse cancers. Here, we evaluated whether genetically modified vaccinia virus (LIVP-GFP) may be...

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Share to Cytopathogenic Effect, Viral
Share to Drug Resistance, Multiple

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Melanoma, Experimental

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Source

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Identifiers

PMID: 27538520
DOI: 10.1186/s12967-016-1002-x
PMCID: PMC4989492

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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