Article
[Inhibitors of JAK2/STAT Signaling Pathway and Hematologic Malignancies-Review].
Zhongguo shi yan xue ye xue za zhi - 1 Aug 2016
Zhao Ya-Ling, Liu Gui-Min, Zhang Li-Jun, Liang Wen-Tong, Cheng Zhi-Yong
Abstract excerpt
Jauns kinase (JAK)/transducer and activator of transcription(STAT) pathway is a classical approach to study the rapid changes of the gene expression in specific target cells by a variety of extracellular signals. The JAK and STAT transfer cytokine receptor signaling plays a unique role in multiple cellular and molecular biological changes.The abnormal signal of JAK/STAT pathway will lead to the hematopoietic...
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