Article
Commonalities in Development of Pure Breeds and Population Isolates Revealed in the Genome of the Sardinian Fonni's Dog.
Genetics - 1 Oct 2016
Dreger Dayna L, Davis Brian W, Cocco Raffaella, Sechi Sara, Di Cerbo Alessandro, Parker Heidi G, Polli Michele, Marelli Stefano P, Crepaldi Paola, Ostrander Elaine A
Abstract excerpt
The island inhabitants of Sardinia have long been a focus for studies of complex human traits due to their unique ancestral background and population isolation reflecting geographic and cultural restriction. Population isolates share decreased genomic diversity, increased linkage disequilibrium, and increased inbreeding coefficients. In many regions, dogs and humans have been exposed to the same natural and...
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