Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro.

International journal of molecular medicine - 1 Oct 2016

Mateu Rosana, Živicová Veronika, Krejčí Eliška Drobná, Grim Miloš, Strnad Hynek, Vlček Čestmír, Kolář Michal, Lacina Lukáš, Gál Peter, Borský Jiří, Smetana Karel, Dvořánková Barbora

Abstract excerpt

Clinical evidence suggests that healing is faster and almost scarless at an early neonatal age in comparison with that in adults. In this study, the phenotypes of neonatal and adult dermal fibroblasts and keratinocytes (nestin, smooth muscle actin, keratin types 8, 14 and 19, and fibronectin) were compared. Furthermore, functional assays (proliferation, migration, scratch wound closure) including mutual...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coculture Techniques
Share to Fibronectins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Keratinocytes

Share to Mesoderm

Share to Myofibroblasts

Share to Nestin

Share to Neural Crest

Share to Neuronal Plasticity

Source

Open in PubMed Open full text

Identifiers

PMID: 27513730
DOI: 10.3892/ijmm.2016.2706
PMCID: PMC5029973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro.PMID 27513730Read ↗

Analysis of dermal fibroblasts isolated from neonatal and child cleft lip and adult skin: Developmental implications on reconstructive surgerySemantic proximity Read ↗

The regenerative capacity of neonatal tissuesSemantic proximity Read ↗

Phenotypic and functional modulation of 20-30 year old dermal fibroblasts by mid- and late-gestational keratinocytes in vitro.Semantic proximity Read ↗

From newborn to adult: phenotypic and functional properties of skin equivalent and human skin as a function of donor age.Semantic proximity Read ↗

Newborn infant skin gene expression: Remarkable differences versus adultsSemantic proximity Read ↗

Progenitor cell properties and the engineering of tissues.Semantic proximity Read ↗

Tissue engineering of skin and corneaSemantic proximity Read ↗

Skin wound healing and scarring: fetal wounds and regenerative restitution.Semantic proximity Read ↗

Age-dependent neuroectodermal differentiation capacity of human mesenchymal stromal cells: limitations for autologous cell replacement strategiesSemantic proximity Read ↗

Chemokine Involvement in Fetal and Adult Wound HealingSemantic proximity Read ↗

Establishment of 3D organotypic cultures using human neonatal epidermal cellsSemantic proximity Read ↗

Differential expression and regulation of extracellular matrix‐associated genes in fetal and neonatal fibroblastsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.